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Overall, GLP1 agonists show central effects on brain regions involved in energy balance and cognition and may act in parallel to, rather than simply downstream of, insulin to modulate neuronal activity and glucose utilization

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29 By contrast, in a study of Liraglutide for weight reduction (in people with type 2 diabetes) participants lost about 6 percent of their body weight, depending on dose

Results Twelve independent single nucleotide polymorphisms were identified as genetic instruments for GLP-1RAs

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