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weight-loss numbers come from members own scale readings, waist-change figures are based on members tape-measure readings, and clothing-size changes reflect members stated apparel sizes

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These findings occurred at clinically relevant exposures and are thought to result from sustained stimulation of calcitonin release from thyroid C-cells, which express GLP-1 receptors in rodents

In diabetic patients on semaglutide who also take insulin or sulfonylureas, this risk slightly elevates

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