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Because it is still investigational and not available in prefilled pens, compounded retatrutide arrives as lyophilized powder that requires manual reconstitution before injection

doi: 10.1016/j.cmet.2019.07.016 19

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Depending on the nature of the request, in line with ethics approval, the study protocol and participant consent form, further approvals may be required from the Joint Research Office (UCL) or NHS Research Ethics Committee