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TMAO promotes apoptosis and oxidative stress of pancreatic acinar cells by mediating IRE1-XBP-1 pathway
Adenofibrosis in the rat liver, with persistence of polychlorinated biphenyls in adipose tissue
reported that inhibition of the Xc- transport system using sulfasalazine, while ineffective as a monotherapy, was highly effective to eliminate AML cell lines when combined with Buthionine sulfoximine (BSO), an inhibitor of glutamyl cysteine synthetase, the first enzyme in the synthesis of GSH
It directly scavenges reactive oxygen species (ROS), thereby reducing oxidative stress and cellular damage
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