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By emphasizing mechanistic insights, this review aims to inform the optimization of personalized weight-loss strategies and guide the development of non-surgical interventions that mimic the metabolic benefits of bariatric surgery [5]
Tesamorelin (Egrifta) is FDA-approved for HIV-associated lipodystrophy
After 36 weeks, the 0.5 mg retatrutide group showed a 3.19% body weight reduction, the 4 mg group showed a 10.37% decrease, the 8 and 12 mg groups demonstrated decreases of 16.81% and 16.94% respectively, which were significantly greater than those observed with placebo (3.00%) and 1.5 mg dulaglutide (2.02%) [114]
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