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Semaglutide was added to WADAs Monitoring Program in 2024, with tirzepatide following in 2025

Adults Over 50 Reduced stomach acid production Decreased ability to absorb B12 from food Common medications that interfere with B12 absorption 4

Subsequent work by Pickart and Margolina identified clusters of affected genes spanning DNA repair, antioxidant defense, ubiquitinproteasome activity, anti-inflammatory signaling, and tissue remodeling [2]

Semaglutide works by activating GLP-1 receptors that deliberately slow how fast your stomach empties