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Life Sci 75, 16491657, 10.1016/j.lfs.2004.05.008 (2004)

Insulin binds to receptors on insulin-sensitive tissues to trigger the uptake of glucose into the cell

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2) Cellular Growth in Human Myotubes In human cell models 4 , IGF-1 directly drives hypertrophy markers (greater nuclei per myotube, higher fusion index, elevated contractile protein content), reinforcing its role in the cellular foundation of strength and size gains