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In addition, scientists are also interested in other potential targets besides M1 in pain treatment (66)
(PubMed) McDonnell MG, Archbold GP
Resistant maltodextrin or fructooligosaccharides promotes GLP-1 production in male rats fed a high-fat and high-sucrose diet, and partially reduces energy intake and adiposity
Downstream effects commonly explored in experimental systems include modulation of IGF-1 signaling, protein synthesis pathways, lipid metabolism markers, and cellular repair processes
Until durability data are available, chronic maintenance therapy analogous to treatment paradigms for other chronic liver conditions is likely required to sustain hepatic benefits
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