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doi:10.1056/NEJMoa2301972 Coskun T, Urva S, Roell WC, Qu H, Loghin C, Moyers JS, O'Farrell LS, Briere DA, Sloop KW, Thomas MK, Pirro V, Wainscott DB, Willard FS, Abernathy M, Morford L, Du Y, Benson C, Gimeno RE, Haupt A, Milicevic Z

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Clinical studies of GHK-Cu combined with 15% L-ascorbic acid demonstrate additive improvements in photoaging parameters, with combination formulations producing 35-45% greater wrinkle reductions than either agent alone

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