For most eligible patients, GLP-1 medications are considered safe when: Prescribed by a licensed healthcare provider Initiated at appropriate doses Gradually titrated Monitored regularly These medications have undergone large clinical trials and have more than a decade of safety data in diabetes management
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acquired malignancy, pregnancy, OCP use, inflammatory disease, heparin-induced thrombocytopenia) Once a thrombus forms, it can propagate proximally (distal to proximal extension, increasing PE risk), embolize to the pulmonary arteries (PE see separate CDG), or undergo fibrinolysis (spontaneous resolution) or organization (becoming chronic/fibrotic)