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Inhibition of BACE-1 by QCN is mediated by suppressing nuclear factor kappa B (NF-B) which induce the expression of BACE-1 protein (Paris et al
Thus, DNTB method grants measurement of free GSH, oxidized GSH (GSSG) and total content of GSH (free GSH + GSSG) in a multi-step approach in biological samples
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