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These medications help regulate appetite by promoting a feeling of fullness and reducing cravings, or as many call it food noise. Many patients report a decrease in overall hunger and a noticeable reduction in their desire for unhealthy, calorie-dense foods

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Tukey Post Hoc comparison indicates a significant increase of microglia ramification in the PL-PFC in VEH-AMPH group compared with the CAND-SAL and CAND-AMPH groups ( p = 0.007 and p = 0.005, respectively) and no significant differences in the comparison between control groups (VEH-SAL and CAND-SAL