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Diabetic retinopathy complications have been observed primarily with semaglutide, particularly with rapid glucose improvement in patients with pre-existing retinopathy, warranting ophthalmologic monitoring in high-risk individuals

Investigational drugs do not yet have the same clinical pathway

Anti-Doping Agency)

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They can be interpreted as the average number of T2D patients who would need to be treated with a GLP-1RA relative to insulin for a given follow-up period of time to prevent one case with a clinical outcome of interest