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The proportion of new users without FDA-approved indications rose from 0.21% to 0.37% from 2019 to 2023

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Semaglutide is similar to a natural GLP1 hormone released after a meal and works on appetitecontrol centres in the brain, helping you feel fuller, less hungry and reducing cravings when combined with a reducedcalorie diet and increased physical activity

doi: 10.3390/ijms20081850 47

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