Clinical trial signals exist, and they deserve context: Sleep Recovery, 2024 documents that in a clinical trial, 7% of patients taking Wegovy reported insomnia as a side effect, a finding that suggests a measurable signal in controlled study conditions, yet does not prove causation for everyone taking the drug
Keep in mind, if you have a family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2), your provider may advise against GLP-1 therapy as a precaution
& Bonnet, P
The signs and symptoms I described earlier, including the sympathetic manifestations of sweating, tremor, and irritability, are the ones we can observe directly
Each report should clearly state the model, timing, comparison group, and measured endpoints