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Leptin resistance can lead to feelings of excessive hunger and sluggish use of stored energy (i.e., fat)

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The SURMOUNT-1 trial [8] involved 2539 obese subjects receiving 5, 10, or 15 mg of tirzepatide versus placebo over 72 weeks

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Previous research has shown that immuno-metabolic dysregulations map more consistently to symptoms of the atypical spectrum characterized by altered energy intake/output (in particular the reversed neurovegetative symptoms of hyperphagia, hypersomnia with leaden paralysis and fatigue) [2] and symptoms of anhedonia [33]

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In addition to the above requirements, Brightmeds LLC and certain affiliated professional entities reserve the right to change or include new requirements as deemed appropriate in their sole discretion without providing prior notice to you

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