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Zimmermann, C
Turn the vial upside down with the needle still in the vial
doi:10.1136/bcr-2018-227644
Folate is a co-factor for enzymes that regulate DNA synthesis and methylation, and is more directly involved in these processes than B12---making it vital for proper gene expression as well as cell growth, repair, and division, especially during periods of rapid growth like pregnancy
16 Furthermore, as these models rely on immunocompromised hosts, they cannot replicate immune-related resistance mechanisms
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