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As cells highly active in the homeostasis of the CNS microenvironment, astrocytes have already been shown to contribute to the pathophysiology of neuroinflammatory and neurodegenerative disorders, such as Alzheimers (85) and Parkinsons diseases (86)

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The Impact of Melatonin on Colon Cancer Cells Resistance to Doxorubicin in an in Vitro Study. International Journal of Molecular Sciences, vol

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Homocysteine may then be converted into cysteine and remethylated into methionine to be used for glutathione

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