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These pathways typically oppose longevity

Just for hard-core geeks, the main biologically active compounds are pentacyclic triterpenoid saponins called asiaticoside, madecassoside, asiatic and madecassic acid (also called centellosides)

Scientists have long recognised the potential benefits of transdermal drug delivery, including improved patient compliance, steady drug release, and avoidance of gastrointestinal degradation and first-pass metabolism