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Who must avoid it entirely in the class framing: anyone pregnant or breastfeeding, anyone with the personal/family MTC or MEN 2 history above, and anyone with prior serious hypersensitivity to a GLP-1 agonist
While scalp allodynia is indeed a form of allodynia (commonly seen with migraines), whole-body skin sensitivity is the pattern associated with semaglutide in the published literature
Yang T, Zhang D
If you are titrating tirzepatide for weight loss and your medication has quietly degraded, you might increase your dose prematurely because you are not getting the expected response at the current level
Professional dosing should always be done
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