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Published research suggests this interaction may be bidirectional, with BPC-157 appearing to promote or counteract NO system effects depending on the experimental context (Sikiric et al., 2014)

doi:10.1186/s13024-016-0082-7 Moore EM, Mander AG, Ames D, Kotowicz MA, Carne RP, Brodaty H, Woodward M, Boundy K, Ellis KA, Bush AI, Faux NG, Martins R, Szoeke C, Rowe C, Watters DA (2013) Increased risk of cognitive impairment in patients with diabetes is associated with metformin

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