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Ayala, J

Neurobiol Pain 12:100102 Younis S, Hougaard A, Vestergaard MB, Larsson HBW, Ashina M (2017) Migraine and magnetic resonance spectroscopy: a systematic review

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At sufficient concentration calcidiol, an intermediate in calcitriol synthesis, can also activate the VDR

Both RFK and FLAD1 reside in the cytosol and within mitochondria, allowing newly formed FAD to accumulate in the mitochondrial matrix, where it serves as an essential co-factor for numerous flavoproteinsincluding ETF-DH, AIFM1, multiple acyl-CoA dehydrogenases, and glutathione reductase (Figure 1) (60)