Sebum production does not decline again until after menopause for women and around the sixth to seventh decade for men.1 Androgens, particularly 5alpha-dihydrotestosterone (DHT), play a major role in the differentiation and proliferation of sebaceous glands as well as sebum production.[5,6] The average rate of sebum production in adults is 1mg/10cm2 every three hours.[7] When rates are less than 0.5mg/10cm2 every three hours, patients can suffer from xerosis or dry skin
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[8] [9] A variety of peripheral nerve cells, including axons, perineurial cells, fibroblasts, and varying inflammatory components such as mast cells and lymphocytes, are also present in neurofibromas

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