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Orlistat: Orlistat (OTC version Alli) and the brand-name medication Xenical work completely differently from other weight-loss medications
Patients with type 2 diabetes, as well as those prescribed these drugs offlabel for weight loss, have reported complications including: Severe gastrointestinal issues Vision loss Rare conditions such as NAION (nonarteritic anterior ischemic optic neuropathy) Complications resembling NAION symptoms If you took Ozempic or a similar GLP1 medication and suffered severe gastrointestinal problemssuch as persistent gastroparesis or other serious issuesyou are not alone
They often lead to bright red blood during or after a bowel movement due to swollen veins in the anal area
Gene 533(2):469476
Known Risks, Side Effects, and Safety Considerations The most common side effects are gastrointestinal including nausea, vomiting, and diarrhoea with additional class-related risks of pancreatitis and gallbladder disease
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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