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Food and Drug Administration (FDA) about these findings and recommends that people using these untested products contact their physicians for advice and discussion on alternative treatment options. The Study Identified a Chemical Reaction Between Tirzeptide and Vitamin B12 Lillys laboratory testing found that the interaction between tirzepatide and vitamin B12 produced a molecule larger than tirzepatide alone a change that could theoretically affect how the drug is absorbed, distributed, metabolized, or eliminated in the body, the study authors wrote

Consistency with supplementation and addressing any underlying health issues are crucial for maximizing the benefits of B12 injections

Similarly, it has specific usage requirements which must be considered and followed

No serious adverse events have been reported across 100+ studies