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You might notice your HRT feels slightly less effective, but the safety profile isnt altered

Adjustments can be made based on real-world results, reinforcing the personalized treatment aspect

The gastrointestinal effects of the medication are well-documented in the SmPC and European Public Assessment Report (EPAR), but hiccups specifically have not been validated through controlled clinical studies

Most patients experience constipation during the first 24 weeks of starting semaglutide or during dose increases, with symptoms typically improving as your body adjusts

Animals were daily administered with equivalent doses (10 nmol/kg) of GLP1/E, GLP1/GIP, or GLP1/GIP/Glucagon for 3 days