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In the SYNERGY-NASH trial, tirzepatide achieved MASH (metabolic dysfunction-associated steatohepatitis) resolution without worsening of fibrosis in 62% of patients at the highest dose (15 mg), compared to 10% for placebo, with dose-dependent responses of 44% at 5 mg and 56% at 10 mg
In contrast, Ozempic (Semaglutide GLP-1) works as a GLP-1 receptor agonist that mimics natural hormones in the body that regulate blood sugar levels after eating
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A study on the frequency of nodal naevi and a discussion of their pathogenesis, including the concept of benign metastasis in which nodal naevi are melanocytes derived from a nearby naevus
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