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For this reason it is initially often started together with colchicine (see above), so that while the matches1 are slowly removed, those remaining are dampened. Other adverse reactions to allopurinol include skin rash, abnormality of liver blood tests, and occasionally a drop in the white blood cell count

Routine Check-ups: Regular blood tests to monitor B12 levels

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High intracellular GSH is associated with drug resistance by promoting drug conjugation and transport-mediated efflux