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CNS tissue has an exceptional ability to take up glutamate via excitatory amino acid transporters (EAATs), leading to a high level of substrate readily available to be converted to -KG (and subsequently 2-HG, with its potential for downstream tumorigenic effects.) This may explain why IDH1 mutations are highly prevalent in many CNS malignancies like GBM and could play an important role in tumor progression
Drinking 23 extra liters of water daily, eating fiber-rich vegetables, and gentle movement like walking can ease this transition without delaying your dose increases
BONUS #1: VIBRATION PLATE SESSION Helps to eliminate the liquified fat cells
Research published in the American Journal of Clinical Nutrition demonstrates this metabolic adaptation persists for years after weight loss, with the body burning 200-500 fewer calories daily than predicted for someone of that weight who was never overweight
to be able to now have them available in peptide therapy when done properly
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