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Rat research found 38.4% oral bioavailability, but no human study has compared the two routes

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Delivery method (injection typically outperforms topical)

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Ruiz et al., 2015), 12 weeks (Forti et al., 2014), and as long as 9 months in individuals with type 2 diabetes (Swift et al., 2012) have not been shown to change basal serum BDNF