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Specific concerns include post-cholecystectomy syndrome (a cluster of persistent GI symptoms in 1015% of patients) and potential interactions between GLP-1-induced motility changes and pre-existing bile acid malabsorption
based on full DCS/EDCS/CARD/OCS IC universe (Targets + Non-Targets)
doi: 10.1016/j.bjps.2023.04.057 Humphrey CD and Lawrence AC
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Coffee has mild prokinetic effects and can stimulate colonic contractions
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