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Gastrointestinal side effects, including nausea, vomiting, diarrhea, and constipation, are common with GLP-1 receptor agonists

Biomolecules 12 (7), 903 (2022)

Are these therapies covered by insurance

Furthermore, clinical trials have reported that 35% to 45% of GLP-1 weight loss is not fat, but lean mass including muscle and bone

However, a retrospective cohort study published in Diabetes Care did find that use of GLP-1 medications for 1-3 years was associated with a slightly increased risk of all thyroid cancer (adjusted hazard ratio 1.58) and medullary thyroid cancer specifically (adjusted hazard ratio 1.78)