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Although poor survival may result from large tumor size [13, 30, 31], inadequate margin [13, 15, 30], high-level tumor grade [13,14,15], or presence of distant metastasis [13, 31, 32], prognostic factors have not reached an agreement in literatures

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By inhibiting Yy1, miR-192-5p decreases FAS levels, leading to lower TG synthesis in the liver