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Specifically, encapsulated strains reduce interleukin8 (IL8) secretion and inhibit Escherichia coli adhesion, while macrophage coculture models report increased IL10 and decreased TNF [177]

Substantial epidemiological evidence has linked chronic exposure to environmental endocrine disruptors to a range of adverse reproductive outcomes in humans, including impaired spermatogenesis in males, diminished ovarian reserve in females, and an increased risk of infertility [100, 101]