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Since LC is still used by the athletes [9, 10], the aim of this systematic review is to evaluate the effect of prolonged LC supplementation on metabolism/metabolic changes in healthy human subjects

In mice fed Se deficient diets, testicular atrophy, reduced diameter of the seminiferous tubules, osseous metaplasia, and reduced spermatogenic activity were observed: no mitotic activity in spermatogonia, reduced the number of spermatogenic cell lines (including stem cells, pachytene spermatocytes, spermatids, and maturing sperms), and higher rates of abnormal morphology of sperm were found without difference in chromosomal abnormalities in spermatocytes (85, 100)

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In some individuals, more severe psychiatric manifestationssuch as depressive disorders, manic episodes, or psychotic symptomshave also been described ( 6.2 Neurobiological and cognitive effects Neurobiological research suggests that AAS exposure may affect central nervous system functioning by inducing both structural and functional alterations

A protein-abundant diet, resistance training, and cardiovascular activities maximize muscle development and fat reduction