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For researchers using oral capsules, taking the compound 30 to 60 minutes before meals in a fasted state may enhance fat oxidation effects, though this recommendation is based on theoretical considerations rather than controlled studies

Seiwerth, S

Because this combination is not approved yet, healthcare providers will eventually closely monitor patients for gastrointestinal side effects, such as nausea, vomiting, or constipation, and adjust doses accordingly to maximize benefits while minimizing discomfort