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the remainder reaches the colon and may be fermented or excreted in faeces
Only 4.2% discontinued due to side effects after week 24
Clinical data indicate that when patients stop taking the medication, the biological suppression of appetite and the regulation of satiety signals are removed
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Br J Clin Pharmacol 12:235246 Marathe PH, Wen Y, Norton J, Greene DS, Barbhaiya RH, Wilding IR (2000) Effect of altered gastric emptying and gastrointestinal motility on metformin absorption
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