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Not recommended for children, teenagers, pregnant and breastfeeding women and outside of meals

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Individuals with Insulin Resistance: Even without a formal diabetes diagnosis, GLP-1 medications might be considered in cases of significant insulin resistance

Following Connecticuts drastic increase in utilization under their state employee health plan, in 2023 the state began requiring enrollees to enroll in a telehealth program that sought to encourage full-scale lifestyle changes and eventually reduce dependence on GLP-1s and similar medications