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Exacerbating the problem, most patients get little to no help with the required lifestyle changes

This review focuses on two prominent dietary strategies whose nutritional profiles may complement semaglutides mechanisms of action: the Mediterranean diet (MD) and very-low-energy ketogenic therapy (VLEKT)

Conversely, people who already present with high anhedonia, for instance, in the context of a depressive illness, may see their symptoms worsening when on GLP-1RAswhich could elucidate some of the studies reporting negative effects associated with these medications in mood and anxiety disorders

Agrawal, A

This was a 68-week study of 445 adults with obesity or overweight who also had knee osteoarthritis