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Nature 459 , 945949 (2009)

doi: 10.1136/annrheumdis-2011-201605 34 LenertAFardoDW

In relation to the risk of developing cancer, a study published in The Journal of Clinical Endocrinology & Metabolism found no significant association between the dose of rhGH, mortality, and cancer incidence, making causality far less likely: Safety concerns have been raised regarding premature mortality, diabetes, neoplasia, and cerebrovascular disease in association with GH therapy

The kidney also rapidly filters small peptides (under ~6 kDa)

Animal gut anatomy and digestive physiology differ from humans, so caution is warranted in extrapolating these findings