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A sedentary lifestyle compounds those effects
Barton ER (2006)
Furthermore, escalated oxidative stress can activate GSK3 [90], contributing to elevated A levels [60] (see Section Unlocking Melatonins Anti-Amyloidogenic Potential ) and hyperphosphorylation of the microtubule-associated protein tau [91, 92] (see Melatonins Potential to Counteract Tau Pathology )
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doi:10.1111/j.1600-0560.1991.tb01542.x
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