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Incretin mimetics have demonstrated safety and efficacy in advanced kidney disease, however multiple studies have shown that use of GLP1-RA have shown improvements in glycemic control, body weight reductions, improved beta cell function, and decreased incidence hypoglycemia as compared to DPP4i in a general diabetes population 26,27,28,29,30,31 , effects which might explain the reduction of acute healthcare utilization observed in this study of patients with CKD treated with GLP1-RA as compared to DPP4i
Single-cell mapping of GLP-1 and GIP receptor expression in the dorsal vagal complex
Rybelsus (semaglutide) [prescribing information]
The Lancet, 402(10396), 1617-1618
The triple therapy arm (prednisone + azathioprine + NAC 600 mg three times daily) was stopped early due to increased harm
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