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CXC motif chemokines are involved in neuronal injury, CXC motif chemokine ligand 2 (CXCL2) expression is significantly increased in HG-induced SCs, CXCL2 knockdown increases SCs viability and reduces cleaved caspase 3/9 expression and associated apoptosis (58)
The difference is that bond cleavage is not achieved by hydrolysis, and computers assume the time consuming task of comparing a multitude of fragments
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Aktas C, Kanter M, Kocak Z
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