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10.3390/biomedicines9080992 153 KimJ.-Y.KimK.-H.LeeW.-R.AnH.-J.LeeS.-J.HanS.-M.et al (2015a)

Published literature going back decades doesn't show significant adverse effects at typical doses

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The scalp is actually a reasonably permeable surface compared to other skin areas, especially when you use a vehicle (the carrier liquid) designed for skin penetration