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Ultimately, 706 participants met the eligibility criteria and were randomly assigned to one of several treatment arms: once-weekly subcutaneous injections of Cagrilintide at doses of 0.3, 0.6, 1.2, 2.4, or 4.5 mg, once-daily liraglutide 3.0 mg, or a volume-matched placebo

Therapeutic intervention At the age of 5 months, wide-based excision and curettage of the area down to the normal bone were done under general anesthesia

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MHC-I promotes apoptosis of GABAergic interneurons in the spinal dorsal horn and contributes to cancer induced bone pain