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Since the N-protective group is an amide, removal of this function might require conditions that would also cleave the just formed peptide bond
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The peptide has shown substantial therapeutic potential in experimental models of inflammatory bowel disease, gastric ulceration, and various gastrointestinal inflammatory conditions
Trinchieri A, Boccafoschi C, Chisena S, De Angelis M, Seveso M
For 24 completing subjects, Study 2 was calculated to have a statistical power of 90%, assuming ratios of 0.95, and within-subject standard deviations on the log-scale of 0.17 for atorvastatin and 0.18 for digoxin
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