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Inject once per week as instructed

It is increasingly recognized that GLP-1 medications are much more effective if used as part of a care program provided by teams experienced in specialized weight management

The patient was started on semaglutide for her diabetes approximately 10 months prior to presentation

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The proposed direct vascular mechanisms, supported by preclinical and clinical data, include the following: Endothelial protection: GLP-1 receptor agonists promote nitric oxide production, vasodilation, and angiogenesis while inhibiting oxidative stress in vascular endothelial cells Plaque stabilization: Reduced matrix metalloproteinase activity prevents fibrous cap degradation