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Cellular Energy and Aging Aging is often described at a cellular level as the accumulation of oxidative damage over time

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The glutaminase encoded by GLS2 can be directly bound and transcriptionally induced by p53, reducing cellular sensitivity to ROS-associated apoptosis, possibly through glutathione-dependent antioxidant defense (Suzuki et al., 2010

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NAD was discovered in the early 20th century by Arthur Harden and William John Young while studying alcoholic fermentation

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