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GHK-Cu acts through three main pathways: epigenetic modulation (4,000+ genes, 31.2% of the genome), stimulation of collagen/elastin/GAG synthesis, and copper transport for the activation of antioxidant SOD and wound-healing enzymes

For in vivo experiments, 1012-week-old female C57/BJ mice (Charles River Laboratories, Wilmington, MA, USA) were purchased and acclimatized for 2 weeks before the initiation of the experiments

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The Journal of Clinical Endocrinology and Metabolism, 96 (1), 150-158

Hepatobiliary Pancreat Dis Int