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For example, rapid weight loss can temporarily affect hormones or cause hair shedding
(54) found that administering GIPR antagonist to healthy humans reduced postprandial insulin secretion and increased glucose excursions more than administering GLP-1R antagonist (GLP-1RA), indicating that endogenous GIP may play a more significant role in stimulating insulin secretion and reducing postprandial plasma glucose excursions compared to endogenous GLP-1
Clarifying your weight loss goals can provide motivation and keep you focused on the bigger picture
Most patients adapt within 24 weeks as their body adjusts to the medication
However, novel promising combination therapies are being developed, including those that couple immunomodulators with drugs that stimulate -cell regeneration in order to restore normoglycaemia
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